Chronic Myeloid Leukemia (CML)

Chronic Myeloid Leukemia (CML)

Chronic Myeloid Leukemia (CML) is a type of blood cancer that originates in the myeloid cells of the bone marrow. It is more commonly diagnosed in adults and progresses more slowly compared to acute leukemias.

Causes and Risk Factors

The exact cause of CML is not well understood, but certain risk factors may increase the likelihood of developing the disease, including genetic mutations such as the Philadelphia chromosome and exposure to high levels of radiation.

Symptoms

Common symptoms of CML include fatigue, fever, night sweats, weight loss, and an enlarged spleen. Symptoms can vary based on the stage and progression of the disease.

Diagnosis

Diagnosis typically involves blood tests to check for abnormal white blood cells and a bone marrow biopsy to confirm the presence of leukemia cells. Genetic tests may also be conducted to identify specific mutations such as the Philadelphia chromosome.

Treatment

Treatment for CML often includes targeted therapy with tyrosine kinase inhibitors, chemotherapy, and sometimes stem cell transplants. The treatment plan depends on factors such as the patient’s age, overall health, and specific characteristics of the leukemia.

Disclaimer

The information provided on this website is for general informational purposes only and is not intended as medical advice. The accuracy of the information presented here is not guaranteed and it should not be relied upon as a substitute for professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any questions you may have about your medical condition or treatment options.